Bug 40994 (reported at https://gitlab.torproject.org/tpo/core/tor/-/issues/40994) has become a fairly serious impediment to running relays. I generally obtain two ipv4 addresses on my machines and the ports I want to use for tor are not available on both addresses. So listening on 0.0.0.0 is not an option for me. And listening on a specific address incurs the serious problem where NoListen even when not specified seems to be assumed without recourse (see discussion at https://v236xhqtyullodhf26szyjepvkbv6iitrhjgrqj4avaoukebkk6n6syd.onion/t/rel...)