Almost never if you use the reduced exit policy or the browser only policy (only allowing 80,443,53).
Now, If you leave all ports open like Conrad and I do on most of our relays, a copyright enforcement company called Irdeto USA (the same people behind Denuvo Game DRM) will send you threats and harassment, ignore your replies, and contact upstreams directly rather than the contact on the SWIP Record - be rich and get your own ASN to get around this. Now, Irdeto's business strategy is a simple one they need only to flood your ISP's abuse department with as many automated DMCA Emails as possible until they get too many to ever hope to respond to and then try to get them to terminate your account. Depending on the ISP it'll work.
Cordially,
Nathaniel Suchy